Botulinum toxin
Medically reviewed by Florian Zekaj, doctor (BIG 49938294301). Last updated 13 October 2026.
Softening wrinkles for a relaxed, fresh look that stays natural.
Botulinum toxin is a purified protein that temporarily relaxes a muscle. The site where it is injected determines the effect of the treatment. Relaxing a muscle responsible for the formation of wrinkles, such as in the frown area, the forehead or the crow's feet, can result in smoother skin and a well-rested appearance. Botulinum toxin can also be used to selectively relax the muscles that pull the eyebrows or corners of the mouth downwards, creating a subtle lifting effect.
In addition to aesthetic treatments, botulinum toxin is also used for various medical indications, such as teeth grinding, excessive sweating and tension-related headaches. The degree of muscle relaxation can be precisely fine-tuned by the doctor by adjusting the dosage. This allows the treatment to be personalised and a natural result to be achieved that suits the patient's wishes.
How much does botox cost at Zclinics?
A botulinum toxin treatment starts at €129 per area, for example the forehead, frown lines or crow's feet. Your consultation is always free and without obligation, and you'll hear exactly what your treatment costs during the intake. See all prices on our prices page.
Side effects and risks
Botulinum toxin has been used for decades and is well tolerated when administered by an experienced doctor. Still, a treatment can cause side effects. They are usually mild and temporary: a small bruise, a mild headache or a slightly heavy feeling in the treated area. Less common are a temporarily drooping eyelid or eyebrow, or slight asymmetry. These fade on their own as the effect wears off, usually within a few weeks. Not sure whether something is normal? Please contact us.
When is botox not suitable?
We don't treat you if you're pregnant or breastfeeding. We also don't treat in case of certain muscle disorders (such as myasthenia gravis), an allergy to any of the ingredients, or an infection in the treatment area. Do you use blood thinners or other medication? Mention it during your consultation and the doctor will discuss with you what is sensible.
Aftercare
- Avoid lying down or bending forward for the first 4 hours.
- Avoid intense physical exercise, saunas, hot baths and too much exposure to sun or heat for the first 24 hours.
- Avoid massaging or firmly touching the treated area for the first 24 hours.
- Avoid alcohol and smoking for the first 24 hours.
- Avoid painkillers such as ibuprofen, naproxen, diclofenac and aspirin for the first 24 hours; if needed, preferably use paracetamol.
- Carefully follow any additional instructions from your doctor.
- Contact the clinic if you have severe pain, increasing swelling, an allergic reaction, clear asymmetry or other unexpected symptoms after the treatment.
Treatment in Deventer
Zclinics
Boxbergerweg 27-29, 7412 BB Deventer
Phone: +31 6 11909856
Open: Monday to Sunday, 09:00 - 18:00 (by appointment)
Get directions
Possibilities
Treatment options
Click on a treatment for more information.
Migraine and headaches
For chronic migraine or tension-related headaches, botulinum toxin can be used to reduce the frequency and severity of the complaints.
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Forehead lines
Botulinum toxin relaxes the muscles that cause forehead lines, so that the lines soften and the forehead gains a fresh, relaxed appearance.
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Frown lines
The frown treatment relaxes the muscles between the eyebrows, so that the frown lines soften and the look gains a more relaxed appearance.
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Brow lift
A brow lift with botulinum toxin relaxes the muscles that pull the eyebrows downwards, creating a subtle lifting effect and a fresher look.
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Crow's feet
Botulinum toxin relaxes the muscle around the eyes, so that crow's feet soften and the look appears fresher.
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Nasal wrinkles / bunny lines
Botulinum toxin relaxes the muscles beside the nose, so that the fine lines around the nose when laughing or frowning are reduced.
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Nose tip lift
Botulinum toxin relaxes the muscle that pulls the nose tip down, creating a subtle lifting effect and a more balanced profile.
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Gummy smile
Botulinum toxin relaxes the muscles that raise the upper lip, so that less gum is visible when smiling and a more balanced smile is created.
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Lip flip
Botulinum toxin relaxes the muscles around the upper lip, so that the lip tilts subtly outwards and looks fuller, without using filler.
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Smoker's lines
Botulinum toxin relaxes the muscles around the mouth, so that fine vertical lines (smoker's lines) subtly soften.
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Mouth-corner lift
Botulinum toxin relaxes the muscles that pull the corners of the mouth down, so that the corners of the mouth are subtly lifted and the face gains a friendlier appearance.
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Teeth grinding / bruxism
Botulinum toxin relaxes the chewing muscle (the masseter), so that teeth grinding and jaw clenching decrease and complaints such as jaw pain and headaches can subside.
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Facial slimming
Botulinum toxin relaxes the chewing muscle, so that the jawline looks subtly slimmer and the facial contour becomes more refined.
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Nefertiti lift
With a Nefertiti lift, the neck muscle is temporarily relaxed with botulinum toxin, so that the jawline gains more definition and the profile is subtly lifted.
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Chin dimpling
Botulinum toxin relaxes the chin muscle, so that a restless chin with dimpling or an orange-peel effect visibly softens.
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Hyperhidrosis / sweaty armpits
Botulinum toxin inhibits the activity of the sweat glands in the armpits, so that excessive sweating is effectively reduced.
More infoFrequently asked questions
Questions about botulinum toxin
Does a botulinum toxin treatment hurt?
The injections feel like a small pinprick and are easy to tolerate. The treatment takes 10 to 15 minutes on average.
When will I see the result?
The effect starts gradually after a few days and is fully visible after about two weeks.
How long does the result remain visible?
On average 3 to 4 months. After that you can repeat the treatment.
Is botulinum toxin safe?
There is a small chance of a complication after a botulinum toxin treatment. The most common side effects are mild redness, temporary swelling, tenderness or a small bruise at the injection site. These usually disappear within a few days. When you are treated by an experienced BIG-registered doctor, the risk of complications is limited.
Can botulinum toxin be dissolved?
No. Unlike filler, botulinum toxin cannot be dissolved. The effect of the treatment disappears by itself after a number of months, as the body clears the botulinum toxin and muscle activity returns.
Interested in this treatment?
Book a free, no-obligation consultation. Our BIG-registered doctors take the time for you and create a tailored plan together with you.